Wednesday, February 3, 2010

New Trigger to Type 2 Diabetes

As you may have know it, the above picture is a a structural form of nicotinamide, or also known as the amide form of nicotinic acid (Vitamin B3 or also popularly known as niacin). Speaking of vitamins, many believe that vitamin is indeed very important elements. Though vitamins are important, we only need them in very scarce amount.

Any excessive amount could cause us hazards. For example, large dosage of vitamin C in our body could cause us problems such as indigestion and also iron poisoning. The same goes for the amide form of nicotinic acid. What could happen if nicotinamide overloads within our body? The consequence -- is none other than triggering the deadly "Type 2 Diabetes".

Based on a recent research article which was published in the World Journal of Gastroenterology, a close association between excessive intake of niacin and type 2 diabetes is linked. The theory behind such postulation, is because a diabetic patient takes a relatively much longer time to completely metabolize nicotinamide in our body. Due to this, high nicotinamide level in the body may increase reactive oxygen generation, in other words, this triggers oxygen stress as well as insulin resistance. When this happens, type 2 diabetes can invade anytime without a doubt.

The liver is an important organ in detoxifying nicotinamide. Hence, when an individual appear to experience liver injuries, many vital functions carried by the liver, including nicotinamide detoxification, will not be able to carry out. As a result, glucose intolerance could also occur.

Niacin can be found in variety of food sources, ranges from liver, chicken, beef, fish, cereal, legumes to dairies and eggs. Excess niacin in our body could poised to be a threat, but is there any other better way to dispose off the unnecessary niacin that we do not need in our body? Surprisingly, this piece of study interestingly demonstrated that sweating could be a very effective way in expelling excess nicotinamide from the body.


  1. Diabetes is a very common disease. The deficiency of insulin leads to type 1 diabetes and the inability of the body to absorb insulin leads to type 2 diabetes. It is commonly found in children and teens. There are many signs and symptoms like fatigue, weakness, excessive urination, weight gain or loss, itching in genital organs etc. Cholesterol, hypertension, obesity are few causes of type 2 diabetes. Regular exercise and right diet helps you to prevent from diabetes. For more details refer Type 2 Diabetes

  2. @Pooja, Type 2 diabetes primarily refers to situations where the insulin hormones in our body have become malfunctioned, and could not work properly. And the type of diabetes which could often found in children and teens is Type 1 Diabetes, not Type 2; this is because Type 1 Diabetes, as you've pointed out, refers to the deficiency of insulin hormones itself, in other words, huge possibilities that it occurs from the very beginning of a human's life.

    Thanks for sharing :)


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